Long COVID - serotonin?
Serotonin levels are depleted in long Covid patients, study says, pointing to a potential cause for
A team led by researchers from the University of Pennsylvania concludes that when long Covid depletes peripheral serotonin — the kind that circulates in our bodies and not just the brain — that deficit impairs memory and other brain functions.
Serotonin reduction in post-acute sequelae of viral
In this study, we perform a metabolomics investigation and find that serotonin levels are a possible discriminator between recovered individuals and Long COVID patients.
One important consequence of peripheral serotonin deficiency is reduced activity of the vagus nerve, which in turn is associated with hippocampal dysfunction and memory loss.
Our findings suggest that many of the current hypotheses for the pathophysiology of PASC might be interconnected and offer actionable therapeutic insights.